Peptides that may help with headaches (including migraines, tension headaches, or chronic pain). several peptides show promise due to their anti-inflammatory, neuroprotective, and vasoregulatory effects.

Epithalon (also called Epithalamin) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) derived from epithalamin, a natural peptide isolated from the pineal gland by Russian scientist Professor Vladimir Khavinson and his team in the 1980s.